Multi-Cancer Early Detection (MCED) Test
What is a Multi-Cancer Early Detection (MCED) Test?
A Multi-Cancer Early Detection (MCED) test is an advanced screening tool that helps identify multiple types of cancer at an early stage, before symptoms appear. At Beacon Hospital, we now offer an innovative ctDNA-based MCED test that only needs a 10mL blood sample for a comprehensive cancer screening.
What is a Circulating Tumour Deoxyribonucleic Acid (ctDNA)?
All cells in the body contain deoxyribonucleic acid (DNA), the molecule that carries the genetic instructions needed for cell growth and function. As cells break down, they release DNA fragments into the bloodstream, known as cell-free DNA (cfDNA).
When cancer cells undergo this process, they release a specific type of cfDNA called circulating tumour DNA (ctDNA). Using advanced next-generation sequencing, ctDNA can be analysed to detect probable presence of cancer to allow for early detection, treatment monitoring, and even identifying signs of recurrence earlier than other tests can through a simple blood test.
Why choose the MCED Test?
The MCED test works differently from conventional tumour marker tests and standard screening programmes. It identifies ctDNA signals that may indicate the early presence of several cancer types before symptoms appear. It offers a quick, minimally invasive way for cancer screening, giving you and your doctor valuable time to act sooner, when treatment may be more effective.
Using SPOT-MAS™ technology, Beacon Hospital’s MCED test offers 78% overall sensitivity in identifying the 10 types of cancers, dependant on the stages of cancer, which include the top five most common cancers in Malaysia:
- Breast
- Lung
- Colorectal
- Stomach
- Liver & biliary tract
- Ovary
- Pancreas
- Oesophageal
- Endometrial
- Head & Neck
A positive result allows for timely follow-up with confirmatory and diagnostic tests (e.g. imaging, medical procedures) and customised treatment planning.
Who should consider taking the MCED test?
- Individuals over 40
- Individuals who are smokers, or consume alcohol regularly
- Individuals who are diabetic
- Carriers of Hepatitis B and C
- Individuals with family history of cancer, even more so if first degree relatives
The MCED test is recommended as an adjunct to your annual health screening.
Early detection is crucial—it can lead to simpler treatment options, better outcomes, and higher survival rates. The MCED test is not a replacement for standard screening methods, but a valuable complement to existing cancer screening tools.
Speak to our doctors to learn if ctDNA MCED test is right for you.